Cefotaxime

Cefotaxime Structure

Specifications of Cefotaxime

Physicochemical Properties: White or almost white crystal powder, Odourless or little off-odor

Density: 1.8 g/ml

Boiling point: / ºC

Melting point: / ºC

Flashing point: / ºC

Product specification: ≥90%

Main Uses: API

Packaging: 25KG net in a cardboard drum with inner aluminum foil bag

Cefotaxime For Injection USP

• Intramuscular Injection of Cefotaxime Antibiotic:

- Gonorrhea: single intramuscular injection of 1g;

- No complications of pneumococcal pneumonia or acute urinary tract infection: 1g each time, twice a day;

- Preoperative prophylactic drugs: preoperative intramuscular injection of 1g 0.5 ~ 1.5h, 1g during the operation, 1g every 6 ~ 8 hours after the operation, until 24h.

• Intravenous Injection:

-Common cefotaxime dosage: 2 ~ 6g, divided into 2 ~ 3 times; Severe infection (such as sepsis, etc.) 2 ~ 3g every 6 ~ 8 hours. The maximum daily cefotaxime dosage is of12g;

-No complications of pneumococcal pneumonia or acute urinary tract infection: 1g every 12 hours;

-Preventive medication during surgery: intravenous injection of 1g 0.5 ~ 1.5h before surgery, 1g during surgery, 1g every 6 ~ 8 hours after surgery, until 24h;

-Dosage of renal insufficiency: the dose reduction of cefotaxime should be adjusted according to the creatinine clearance rate in patients with severe renal dysfunction;

-Dose during dialysis: 0.5 ~ 2g per day for hemodialysis patients, but the cefotaxime dose should be added once after dialysis.

• Intravenous Injection of Cefotaxime Antibiotic for Children:

(1) Newborns: the age is less than or equal to 7 days, 50mg/kg every 12 hours; 50mg/kg every 8 hours for those over 7 days of age;

(2) for children over 1 month: 50mg/kg every 8 hours, the dose can be increased to 75mg/kg every 6 hours in the treatment of meningitis.

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