Galacto-oligosaccharides Are Beneficial for Improving Sleep

Galacto-oligosaccharides Are Beneficial for Improving Sleep

Galacto-oligosaccharides can be beneficial for improving sleep, mainly through the following indirect pathways:

1. Regulating intestinal flora: There is a close connection between the microbial community in the intestine and the brain. As a prebiotic, galacto-oligosaccharides can promote the growth and reproduction of beneficial bacteria such as bifidobacteria and lactobacilli in the intestine, inhibit the growth of harmful bacteria, and improve the intestinal microecological environment. Short-chain fatty acids (such as butyric acid, acetic acid, and propionic acid) produced by beneficial bacteria in the intestine can not only provide energy for intestinal cells, but also reach the brain through blood circulation, affecting the synthesis and release of neurotransmitters, thereby having a positive effect on sleep. For example, butyric acid has anti-inflammatory and neuromodulatory effects, which helps maintain the stability of the nervous system and promotes sleep.

2. Influence the neurotransmitters: Intestinal microorganisms can participate in the synthesis of a variety of neurotransmitters, such as serotonin (5-hydroxytryptamine), γ-aminobutyric acid, etc. These neurotransmitters are essential for sleep regulation. Serotonin is an important neurotransmitter that plays a key role in regulating mood, sleep, and appetite. About 95% of serotonin is synthesized in the intestine. By improving intestinal flora, galacto-oligosaccharides may promote the synthesis and secretion of serotonin, thereby improving sleep quality. γ-aminobutyric acid is an inhibitory neurotransmitter that can inhibit the excitability of neurons, making people feel relaxed and peaceful, and helping to fall asleep and maintain sleep. Beneficial bacteria in the intestine can synthesize γ-aminobutyric acid. By promoting the growth of beneficial bacteria, galacto-oligosaccharides can indirectly increase the production of γ-aminobutyric acid.

3. Reduce intestinal inflammation: Intestinal inflammation may interfere with the normal function of the gut-brain axis and affect sleep. Galacto-oligosaccharides regulate intestinal flora, enhance intestinal barrier function, and reduce the entry of harmful substances into the blood, thereby reducing intestinal inflammatory reactions. When intestinal inflammation is relieved, the overall state of the body is improved, and sleep quality will be improved.

4. Improve digestive function: Galacto-oligosaccharides can promote intestinal peristalsis, improve digestive function, and reduce the occurrence of discomfort symptoms such as indigestion, bloating, and abdominal pain. Good digestion can make people feel more comfortable at night, reduce sleep interruptions caused by gastrointestinal discomfort, and thus improve the continuity and quality of sleep.

Although GOS can help improve sleep, sleep quality is also affected by a variety of factors, such as living habits, psychological state, environmental factors, etc. Therefore, while improving sleep by taking GOS, people should also pay attention to maintaining a healthy lifestyle and a good mental state.